- Safety Beach to Melbourne Central
- San Remo to Melbourne Central
- Sandhurst to Melbourne Central
- Sandringham to Melbourne Central
- Scoresby to Melbourne Central
- Seabrook to Melbourne Central
- Seaford to Melbourne Central
- Seaholme to Melbourne Central
- Seddon to Melbourne Central
- Sherbrooke to Melbourne Central
- Shoreham to Melbourne Central
- Silverleaves to Melbourne Central
- Skye to Melbourne Central
- Smiths Beach to Melbourne Central
- Somers to Melbourne Central
- Somerton Park to Melbourne Central
- Somerton to Melbourne Central
- Somerville to Melbourne Central
- Sorrento to Melbourne Central
- South Geelong to Melbourne Central
- South Kingsville to Melbourne Central
- South Melbourne to Melbourne Central
- South Morang to Melbourne Central
- South Wharf to Melbourne Central
- South Yarra to Melbourne Central
- Southbank to Melbourne Central
- Spotswood to Melbourne Central
- Springvale South to Melbourne Central
- Springvale to Melbourne Central
- St Albans Park to Melbourne Central
- St Albans to Melbourne Central
- St Andrews Beach to Melbourne Central
- St Helena to Melbourne Central
- St Kilda East to Melbourne Central
- St Kilda West to Melbourne Central
- St Kilda to Melbourne Central
- St Leonards to Melbourne Central
- Strathmore Heights to Melbourne Central
- Strathmore to Melbourne Central
- Sunbury to Melbourne Central
- Sunshine North to Melbourne Central
- Sunshine West to Melbourne Central
- Sunshine to Melbourne Central
- Surf Beach to Melbourne Central
- Surrey Hills to Melbourne Central
- Sydenham to Melbourne Central
- Melbourne Airport to Melbourne Central
- Melbourne Central to Safety Beach
- Melbourne Central to San Remo
- Melbourne Central to Sandhurst
- Melbourne Central to Sandringham
- Melbourne Central to Scoresby
- Melbourne Central to Seabrook
- Melbourne Central to Seaford
- Melbourne Central to Seaholme
- Melbourne Central to Seddon
- Melbourne Central to Sherbrooke
- Melbourne Central to Shoreham
- Melbourne Central to Silverleaves
- Melbourne Central to Skye
- Melbourne Central to Smiths Beach
- Melbourne Central to Somers
- Melbourne Central to Somerton Park
- Melbourne Central to Somerton
- Melbourne Central to Somerville
- Melbourne Central to Sorrento
- Melbourne Central to South Geelong
- Melbourne Central to South Kingsville
- Melbourne Central to South Melbourne
- Melbourne Central to South Morang
- Melbourne Central to South Wharf
- Melbourne Central to South Yarra
- Melbourne Central to Southbank
- Melbourne Central to Spotswood
- Melbourne Central to Springvale South
- Melbourne Central to Springvale
- Melbourne Central to St Albans Park
- Melbourne Central to St Albans
- Melbourne Central to St Andrews Beach
- Melbourne Central to St Helena
- Melbourne Central to St Kilda East
- Melbourne Central to St Kilda West
- Melbourne Central to St Kilda
- Melbourne Central to St Leonards
- Melbourne Central to Strathmore Heights
- Melbourne Central to Strathmore
- Melbourne Central to Sunbury
- Melbourne Central to Sunshine North
- Melbourne Central to Sunshine West
- Melbourne Central to Sunshine
- Melbourne Central to Surf Beach
- Melbourne Central to Surrey Hills
- Melbourne Central to Sydenham
- Melbourne Central to Melbourne Airport